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Additionally, the American College of Rheumatology released guidelines in 2020 encouraging women with rheumatic diseases to breastfeed if they so desire and are able to do so. The ACR also recommends that lactation-compatible medications be used to manage disease and that individualized risks and benefits be reviewed with each patient
In a small open-label trial of exenatide in people with clozapine-associated obesity (BMI 3045 kg/m 2 ), those on exenatide had about 10 pounds more weight loss than placebo at 24 weeks (Siskind D et al, J Psychiatr Res 2020;124:912)
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Many of the patients who received vials of compounded semaglutide lacked experience with self-injections
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